Book through our site
—up to 10% cheaper
than Booking.com
Check rooms and rates
From72US$ /night
Check-in
15Mar2026Select date
Check-out
16Mar2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

5130 Vantage Way, San Antonio, Texas, United States, 78249
-
Near the entertainment district
Great
8.3
7.9
/10
3.8
3.2
/5

Location

Comfort Suites Medical Center is strategically located near the prestigious Texas Medical Center and just minutes from Six Flags Fiesta Texas. The hotel provides convenient access to major highways, making it easy to explore San Antonio's attractions. Guests can reach popular sites such as SeaWorld San Antonio and the historic Alamo within a short drive.

Rooms

The hotel offers 150 spacious suites designed to accommodate families and business travelers alike. Each suite includes a separate living area, a refrigerator, and a microwave for added convenience. Accessible and mobility-friendly suites are available, catering to a range of guest needs.

Dining

A complimentary hot breakfast is available daily, featuring a variety of options such as eggs, sausage, and fresh fruit. Guests can enjoy the convenience of a 24-hour market for snacks and beverages. Dining options are also nearby, including popular restaurants that suit diverse tastes.

Family Amenities

Children can enjoy the outdoor swimming pool, providing a fun area for relaxation and play. The hotel also offers spacious rooms that allow families to stay together comfortably. Other family-friendly amenities include a game room, ensuring entertainment for younger guests during their stay.

Business Services

The hotel features a well-equipped business center for guests needing to attend to work-related tasks. Meeting space is available, accommodating various corporate gatherings and events. Additional services include fax and copy capabilities, ensuring that business needs are met efficiently.

Highlights

Location: Near Texas Medical Center, 5 min from Six Flags

Rooms: 150 spacious suites with separate living areas

Dining: Complimentary hot breakfast served daily

Family: Outdoor swimming pool & game room

Business: Meeting space & business center available

“Comfort Suites Medical Center emphasizes family convenience, from its proximity to Six Flags to its kid-friendly breakfast options. The indoor pool allows year-round fun, while meeting spaces cater to business needs, creating a balance of leisure and utility. Its community-focused atmosphere and recent renovations suggest a reliable choice in San Antonio.”
Hotel logo
James DavidEditor-in-Chief at Cheaphotels
View all

Select your room type

The hotel provides a selection of rooms—doubles, family rooms, and suites—with perks like free cancellation, breakfast options, and great value deals
King Suite Accessible or Non-Smoking
2 persons
280 sq. feet 
1 King-size bed and 1 Sofa bed
Shower
Heating
Queen Suite Two Queen Beds Accessible or Non-Smoking
2 persons
305 sq. feet 
2 King Size Beds
Shower
Heating
King Suite Non-Smoking
2 persons
280 sq. feet 
1 King-size bed and 1 Sofa bed
Heating
Queen Suite Two Queen Beds Non-Smoking
2 persons
305 sq. feet 
2 King Size Beds
Heating
Click button to see more rooms
Show all rooms
Show all roomsLess

Room rates & availability calendar

See the best prices and book your dates today!

Amenities & services

Real traveler stories and honest reviews—no glossy ads, just authentic feedback to guide your booking
Facilities: Very good
7.8/10Review score

General

  • No smoking on site
  • Wi-Fi
  • Parking
  • 24-hour reception
  • VIP check-in/ -out
  • Express check-in/ -out
  • No pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Lift
  • ATM/Cash machine
  • Smoke detectors

Sports & Fitness

  • Fitness centre

Children

  • Cots

Facilities for people with disabilities

  • Toilet for disabled

Spa & Leisure

  • Indoor swimming pool
  • Jacuzzi

Room features

  • Air conditioning
  • Sitting area
  • Tea and coffee facilities
  • Ironing facilities

Media

  • Mobile phone charger
Show more

Comfort Suites Medical Center Near Six Flags Location

5130 Vantage Way, San Antonio, Texas, United States, 78249
Map view
5130 Vantage Way, San Antonio, Texas, United States, 78249
Nearby
Huebner Oaks Center
1600 ft
Restaurants
Garbanzo Mediterranean Grill
3900 ft
11075 Huebner Oaks
Bei Fang Chinese Restaurant
2700 ft
11040 Frontage Rd #102
Salata
4300 ft
11075 W IH-10 West Ste. 310
Explore San Antonio
Local Highlights
Top Attractions
Activities
Dining
Entertainment
Six Flags Fiesta Texas
Six Flags Fiesta Texas
15-minute drive
A thrilling theme park featuring exciting rides, live entertainment, and delightful shows for all ages.
Huebner Oaks Center
13 minutes' walk
A vibrant shopping and dining destination perfect for leisurely strolls, featuring various shops and eateries.
Extreme Escape
5-minute drive
An exhilarating escape room experience that challenges problem-solving skills with exciting scenarios.
Orsinger Park
25 minutes walking
A scenic park for relaxing walks, picnics, and enjoying nature, perfect for families and solo visitors.
Garbanzo Mediterranean Grill
Garbanzo Mediterranean Grill
14 minutes' walk
Casual Mediterranean dining with fresh, healthy dishes and plenty of vegetarian options available.
Bei Fang Chinese Restaurant
Bei Fang Chinese Restaurant
10 minutes' walk
Cozy spot serving authentic Chinese cuisine with signature dishes like Kung Pao chicken and dumplings.
Regal Huebner Oaks Stadium 14
5-minute drive
Modern cinema featuring the latest blockbusters, with comfortable seating and a family-friendly atmosphere.
Crystal Ice Palace
5-minute drive
A fun ice skating rink offering sessions for all ages and skill levels, along with special events throughout the year.
Getting around town
City Centre
San Antonio20 min  ·  8.1 mi
Airports
San Antonio International Airport (SAT)26 min  ·  10.4 mi
Train
Southern Pacific Railroad Passenger Station27 min  ·  11.1 mi
Bus
Bus stop3 min  ·  700 ft
Looking for early-bird discounts?
Get special discounted rates today!
Check Rates
Property information and rules
Check-in
from 15:00-23:59
Check-out
until 11 am
Guest Parking
Public parking is possible on site for free.
Internet
Wireless internet is available in for free.
Breakfast
All visitors are offered a buffet breakfast for a fee. 
Pets
Pets are not allowed.
Number of rooms:
86
Former name
Comfort Suites Near UT Health Science Center

Reviews and Ratings

What past guests shared about their stay
Review score
Based on 693 verified reviews
7.5/10
Very good
71%
Recommend
Breakfast
7.7/10
Cleanliness
7.9/10
Comfort
7.9/10
Facilities
7.8/10
Free Wi-Fi
8.3/10
Location
8.5/10
Paid Wi-Fi
7.5/10
Staff
8.4/10
Value for money
8.1/10
Pros
Clean rooms
Comfortable bed
Great breakfast
Great location
Friendly staff
Cons
Black mold
Musty carpets
Security issues
Outdated facilities
Guest reviews
based on 1690 reviews
8.3/10
No reviews yet on our siteUnfortunately, our guests have not yet left any reviews for this hotel, but you can read reviews from Booking.com.
Open reviews
FAQs
About Comfort Suites Medical Center Near Six Flags
What are the check-in and check-out times at Comfort Suites Medical Center Near Six Flags?
Check-in is at 15:00 and check-out is at 11:00.
Is parking available at Comfort Suites Medical Center Near Six Flags?
Free on-site public parking is available without a reservation.
What are the nearby attractions from Comfort Suites Medical Center Near Six Flags?
Nearby attractions include Six Flags Fiesta Texas (6 km), The Alamo (12 km), and the San Antonio River Walk (12 km).
What amenities are available in the rooms at Comfort Suites Medical Center Near Six Flags?
Rooms include a flat-screen TV, coffee machine, microwave, refrigerator, and free Wi-Fi.
Does Comfort Suites Medical Center Near Six Flags offer breakfast?
Complimentary breakfast is provided every morning.
What facilities are available for recreation at Comfort Suites Medical Center Near Six Flags?
Guests can enjoy a heated indoor pool, hot tub, and fitness center.
Is there a business center at Comfort Suites Medical Center Near Six Flags?
A business center with fax and photocopying services is available.
What languages are spoken by the staff at Comfort Suites Medical Center Near Six Flags?
The staff speaks English and Spanish.
Are there dining options near Comfort Suites Medical Center Near Six Flags?
Nearby restaurants include La Madeleine French Bakery, Garbanzo Mediterranean Grill, Fire Wok, Salata, and Luce Ristorante e Enoteca, all within 1 km.
How far is Comfort Suites Medical Center Near Six Flags from San Antonio International Airport?
The hotel is 20 km from San Antonio International Airport.

Next best alternative

Consider them for your next trip.
Check-in
15Mar2026Select date
Check-out
16Mar2026Select date
Rooms and Guests2 Guests, 1 Room